Publications
2022
Hummel, D., Becks, A., Meng, H., Bryda, E, Glasco, D., and Chandrasekhar, (2022) Celsr1 Suppresses Wnt5a-Mediated Chemoattraction to Prevent Incorrect Rostral Migration of Facial Branchiomotor Neurons. Development : 149: dev200553.
2021
Asante, E., Hummel, D., Gurung, S., Kassim, Y. M., Al-Shakarji, N. M., Palaniappan, K., Sittaramane, V. and Chandrasekhar, A., (2021) Defective neuronal positioning correlates with aberrant motor circuit function in zebrafish. Frontiers in Neural Circuits : 15: article 690475.
2019
Liu, F., Dai, S., Peng, X., Qin, Z., Kearns, A. C., Huang, W., Chen, Y., Ergun, S., Rappaport, J., Bryda, E., Chandrasekhar, A., Aktas, B., Hu, H., Chang, S. L., Gao, B. and Qin, X., (2019) Versatile Cell Ablation Tools and their Applications. Cellular and Molecular Life Sciences : 76: 4725-4743.
Ferguson, R., Holloway, D. E., Chandrasekhar, A., Ravi Acharya, K. and Subramanian, V., (2019) The catalytic activity and secretion of zebrafish RNases are essential for their in vivo function in motor neurons and vasculature. Scientific Reports : 9: 1107.
2018
Gurung, S., Asante, E., Hummel, D., Williams, A., Feldman-Schultz, O., Halloran, M., Sittaramane, V. and Chandrasekhar, A., (2018) Distinct roles for the cell adhesion molecule Contactin2 in the development and function of neural circuits in zebrafish. Mechanisms of Development : 152: 1-12.
Kassim, Y. M., Al-Shakarji, N. M., Asante, E., Chandrasekhar, A. and Palaniappan, K., (2018) Dissecting branchiomotor neuron circuits in zebrafish - Toward high-throughput automated analysis of jaw movements. IEEE International Symposium on Biomedical Imaging (ISBI): 943-947.
2017
Chandrasekhar, A., Guo, S., Masai, I., Nicolson, T. and Wu, C-F., (2017) Zebrafish: from genes and neurons to circuits, behavior and disease. Journal of Neurogenetics : 31: 59-60.
Allen, J., Bhattacharyya, K., Asante, E., Almadi, B., Davis, J., Schafer, K., Cox, J., Voigt, M., Viator, J. and Chandrasekhar, A., (2017) Role of branchiomotor neurons in controlling food intake of zebrafish larvae. Journal of Neurogenetics : 31: 128-137.
2016
Glasco, D. M., Pike, W., Qu, Y., Reustle, L., Misra, K., Di Bonito, M, Studer, M., Fritzsch, B., Goffinet, A., Tissir, F. and Chandrasekhar, A., (2016) The atypical cadherin Celsr1 functions non-cell autonomously to block rostral migration of facial branchiomotor neurons in mice. Developmental Biology : 417: 40-49.
2015
Roszko, I., Sepich, D. S., Jessen, J. R., Chandrasekhar, A. and Solnica-Krezel, L., (2015) A dynamic intracellular distribution of Vangl2 accompanies cell polarization during zebrafish gastrulation. Development : 142: 2508-2520.
Bhattacharyya, K., Eshein, A., Chandrasekhar, A. and Viator, J. (2015) Quantitative photoacoustics to measure single cell melanin production and nanoparticle attachment. Physics in Medicine and Biology : 60: 3081-3096.
2014
Yang, T., Jia, Z., Bryant-Pike, W., Chandrasekhar, A., Murray, J. C., Fritzsch, B. and Bassuk, A. G. (2014) Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations. Molecular Genetics and Genomic Medicine 2(2): 138-151.
Pan, X., Sittaramane, V., Gurung, S., Chandrasekhar, A. (2014) Structural and temporal requirements of Wnt/PCP protein Vangl2 function for convergence and extension movements and facial branchiomotor neuron migration in zebrafish. Mechanisms of Development 131(1): 1-14.
2013
Sittaramane, V., Pan, X., Glasco, D.M., Huang, P., Gurung, S., Bock, A., Li, S., Wang, H., Kawakami, K., Matise, M.P., Chandrasekhar, A. (2013) The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function. Developmental Biology 382 (2): 400-412.
2012
Glasco, D.M., Sittaramane, V., Bryant, W., Fritzsch, B., Sawant, A., Paudyal, A., Stewart, M., Andre, P., Cadete Vilhais-Neto, G., Yang, Y., Song, M.-R., Murdoch, J.N., Chandrasekhar, A. (2012). The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled. Developmental Biology 369(2): 211-222.
Thoby-Brisson, M., Bouvier, J., Glasco, D.M., Stewart, M.E., Dean, C., Murdoch, J.N., Champagnat, J., Fortin, G., Chandrasekhar, A. (2012). Brainstem respiratory oscillators develop independently of neuronal migration defects in the WNT/PCP mouse mutant looptail. PLoS ONE 7(2): e31140.
2011
Burroughs-Garcia, J., Sittaramane, V., Chandrasekhar, A., Waters, S.T. (2011) Evolutionarily conserved function of Gbx2 in anterior hindbrain development. Developmental Dynamics 240(4): 828-838.
2010
Bingham. S., Sittaramane, V., Mapp, O., Patil, S., Prince, V., and Chandrasekhar, A. (2010) Multiple mechanisms mediate motor neuron migration in the zebrafish hindbrain. Developmental Neurobiology 70: 87-99.
Bouvrette, D., Sittaramane, V., Heidel, J., Chandrasekhar, A. and Bryda, E. (2010) Knock-down of Bicaudal C in the zebrafish causes cystic kidneys: A new non-mammalian model of polycystic kidney disease. Journal of Comparative Medicine 60: 96-106.
Qu, Y.*, Glasco, D. M.*, Zhou, L., Sawant, A., Ravni, A., Fritzsch, B., Dumrau, C., Murdoch, J. N., Evans, S., Pfaff, S. L., Formstone, C., Goffinet, A., Chandrasekhar, A.* and Tissir, F.* (2010) Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. Journal of Neuroscience 30(28): 9392-9401.
2009
Sittaramane, V., Sawant, A., Wolman, M., Maves, L., Halloran, M. and Chandrasekhar, A. (2009) The cell adhesion molecule Tag1, transmembrane protein Stbm/Vangl2, and Laminina1 exhibit genetic interactions during migration of facial branchiomotor neurons in zebrafish. Developmental Biology 325: 363-373.
2008
Sittaramane, V. and Chandrasekhar, A. (2008) Expression of unconventional myosin genes during neuronal development in zebrafish. Gene Expression Patterns 8: 161-170.
Wolman, M., Sittaramane, V., Essner, J., Yost, H., Chandrasekhar, A. and Halloran, M. (2008) Transient axonal glycoprotein-1 (TAG-1) and laminin-alpha1 regulate dynamic growth cone behaviors and initial axon direction in vivo. Neural Development 3: 6-20.
2005
Vanderlaan G., Tyurina O, Karlstrom R. and Chandrasekhar, A. (2005) Gli function is essential for motor neuron induction in zebrafish. Developmental Biology 282: 550-570. PDF
Bingham, S., Touissant, G., and Chandrasekhar, A. (2005) Neuronal development and migration in zebrafish hindbrain explants. Journal of Neuroscience Methods 149: 42-49.
2004
Chandrasekhar, A. (2004) Turning heads: Development of vertebrate branchiomotor neurons. Developmental Dynamics 229: 143-161.
Teraoka, H., Russell, C., Regan, J., Chandrasekhar, A., Concha, M. L., Yokoyama, R., Higashi, K., Takeuchi, M., Dong, W., Hiraga, T., Holder, N. and Wilson, S. W. (2004) Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos. Journal of Neurobiology 60: 275-288.
2003
Bingham, S., Chaudhari, S., Vanderlaan, G., Itoh, M., Chitnis, A. and Chandrasekhar, A. (2003) The neurogenic phenotype of mind bomb mutants leads to severe patterning defects in the zebrafish hindbrain. Developmental Dynamics 228: 451-463.
2002
Bingham, S., Higashijima, S., Okamoto, H. and Chandrasekhar, A. (2002) The zebrafish trilobite gene is essential for tangential migration of branchiomotor neurons. Developmental Biology 242: 149-160.
Jessen, J. R., Topczewski, J., Bingham, S., Sepich, D.S., Marlow, F., Chandrasekhar, A. and Solnica-Krezel, L. (2002) Zebrafish trilobite reveals new roles for Strabismus in gastrulation and neuronal movements. Nature Cell Biology :4: 610-615.
2001
Bingham, S., Nasevicius, A., Ekker, S.C. and Chandrasekhar, A. (2001) Sonic hedgehog and tiggy-winkle hedgehog cooperatively induce zebrafish branchiomotor neurons. Genesis 30: 170-174.
1999
Warren, J. T., Jr., Chandrasekhar, A., Kanki, J. P., Rangarajan, R., Furley, A. and Kuwada, J. Y., (1999) Molecular cloning and developmental expression of a zebrafish axonal glycoprotein similar to TAG-1. Mechanisms of Development 80: 197-201.
Yee, C.S., Chandrasekhar, A., Halloran, M.C.,Shoji, W., Warren, J. T., Jr. and Kuwada, J.Y., (1999) Molecular analysis, expression, and activity of zebrafish semaphorin Z1a. Brain Research Bulletin 48: 581-593.
Chandrasekhar, A., Schauerte, H., Haffter, P. and Kuwada, J. Y. (1999) The zebrafish detour gene is essential for cranial but not spinal motor neuron induction. Development 126: 2727-2737.
1998
Chandrasekhar, A., Warren, J. T., Jr., Takahashi, K., Schauerte, H., van Eeden, F. J. M., Haffter, P. and Kuwada, J. Y., (1998) Role of sonic hedgehog in branchiomotor neuron induction in zebrafish. Mechanisms of Development 76: 101-115.
1997
Chandrasekhar, A., Moens, C. B., Warren, J. T., Jr., Kimmel, C. B. and Kuwada, J. Y., (1997) Development of branchiomotor neurons in zebrafish. Development 124: 2633-2644.